Cisplatin and radiation
WebCisplatin (cis-diamminedichloroplatinum) has been reported to enhance the cell-killing effect of radiation, an effect whose intensity … WebNov 1, 2004 · A total of 454 cisplatin cycles were administered (median 4 cycles/patient, range 1-6). Overall, 74% of patients received at least four cycles of cisplatin. The …
Cisplatin and radiation
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WebAug 1, 1996 · Purpose: Human glioma cell lines resistant (U373MGCP) and sensitive (U373MG) to cisplatin were used to evaluate the effect of cisplatin as a sensitizer to … WebAug 11, 2011 · ARM II: Patients receive cisplatin and undergo external-beam radiation and brachytherapy as in arm I. Beginning 4 weeks later, patients also receive adjuvant …
WebApr 14, 2024 · In order to find the most significant changes between ABs induced by cisplatin and ABs induced by UV light, partial least squares-discriminant analyses (PLS-DA) were performed for both sequences. Unlike PCA, PLS-DA is a supervised multivariate analysis that relies on the class membership of each observation. WebFeb 16, 2016 · All patients were treated with high-dose cisplatin CCRT. The main outcome parameters were nephrotoxicity (defined as creatinine clearance grade 2 or more) and …
WebCisplatin is believed to augment the effects of radiation by inhibiting the repair of radiation-induced sublethal damage and by sensitizing hypoxic cells to radiation. 9,30 … WebApr 12, 2024 · Currently, gemcitabine/cisplatin is first-line therapy for advanced iCCA based on the ABC-02 clinical trial (ClinicalTrials.gov identifier NCT02170090). That phase 3 study included 410 patients with locally advanced or metastatic CCA, gallbladder cancer, or ampullary cancer.
WebAug 14, 2024 · The U.S. Food and Drug Administration has previously approved cetuximab with radiation for patients with head and neck cancer, including oropharyngeal cancer. Cetuximab with radiation is an accepted standard of care, especially for patients who cannot tolerate cisplatin.
WebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). … high school get to know you gamesWebLocally advanced squamous cell carcinoma of the head and neck: Approaches combining chemotherapy and radiation therapy … trial, weekly cisplatin as part of definitive chemoradiation had noninferior locoregional control (LRC) and was better tolerated compared with bolus cisplatin . The efficacy of cisplatin is also dose dependent … high school get to know you questionsWebObjectives: To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic response … high school get togetherWebApr 12, 2024 · The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely because of advances in immunotherapy. how many chicken breasts in a poundWebInterventions Patients were randomized to weekly concurrent cisplatin (50 mg/m 2), paclitaxel (25 mg/m 2), and daily radiation of 50.4 Gy/1.8 Gy fractions with or without … how many chicken breasts in a cupWebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, … how many chicken breasts is 20 ozWebCisplatin-based concurrent chemoradiotherapy (CCRT) has become a standard treatment for cancer of the uterine cervix. However, there have been no investigations into the optimum timing for administration of anticancer drugs using animal models. high school get to know you activities