Flotillin family protein

WebOct 4, 2005 · May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. Sequence similarities. Belongs to the band 7/mec-2 family. Flotillin subfamily. Cellular localization. Cell membrane. Membrane > caveola. Melanosome. Endosome. Membrane-associated … WebFlotillin-1 Antibody detects endogenous levels of total flotillin-1 protein. Species Reactivity: Human, Mouse, Rat, Monkey. ... Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry an …

Purified Mouse Anti-Flotillin-1 - BD Biosciences

WebAll lanes : Anti-Flotillin 1 antibody (ab41927) at 1 µg/ml Lane 1 : Lung (Human) Tissue Lysate Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 3 : Human brain tissue lysate - total protein Lysates/proteins at 10 µg per lane. Secondary All lanes : IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution Performed … WebFeb 9, 2024 · The flotillin (FLOT)/reggie protein family is integral membrane element and contains two isoforms: flotillin-1 (reggie-2) and flotillin-2 ... Here, we demonstrate that the scaffold protein flotillin-1 … northern talent cup wiki https://retlagroup.com

What is flotillin-associated endocytosis? MBInfo

WebBackground & aims: The flotillin family of proteins, including flotillin-1 (FLOT1 or Reggie-2), are lipid raft proteins that initiate receptor kinase signaling and are up-regulated in several tumor types. We investigated the role of FLOT1 signaling and activation of the transcription factor nuclear factor (NF)-κB in esophageal squamous cell carcinoma … WebNov 28, 2024 · The flotillin family is composed of two highly homologous members: flotillin-1 (flot-1 or reggie-2) and flotillin-2 (flot-2 or reggie-1) 12. Both members of the family are ubiquitously expressed ... WebSep 18, 2012 · The family of flotillin proteins consists of two homologous members, flotillin-1 and flotillin-2, also termed “reggies”, with flotillin-1 being identical to reggie-2 and flotillin-2 to reggie-1 , . Flotillins are … how to run pentaho job from command line

Flotillin proteins could help plant cells maintain their salt …

Category:Flotillin-1 promotes tumor necrosis factor-α receptor ... - PubMed

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Flotillin family protein

Flotillins and the PHB domain protein family: rafts, worms …

WebNov 27, 2009 · Calcium spiking appears to control activity of a calcium/calmodulin-dependent protein kinase and two downstream GRAS-family transcription factors, NSP1 and NSP2, which interact in the plant nucleus and directly bind the ... which contains the protein flotillin . Flotillins [also called Reggies (11)] are often used as markers for ... WebThe formation of lateral microdomains is emerging as a central organizing principle in bacterial membranes. These microdomains are targets of antibiot…

Flotillin family protein

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WebDec 1, 2011 · The flotillin family is composed of two highly homologous proteins, flotillin 1 (also called reggie 2) and flotillin 2 (also referred to as reggie 1) that share ~50% amino acid sequence identity ().They form part of a larger family of proteins that are … WebFlotillin 2 is a direct transcriptional target of the p53 family member genes in human cancer cells. The interaction of flotillin-2 with amyloid precursor protein (APP) promotes the clustering of APP at the cell surface. Coassembly of flotillin1 and flotillin2 into microdomains induces membrane curvature, the formation of plasma-membrane ...

WebMar 1, 2013 · We will not only review the well-known members of the family, such as kinase suppressor of Ras (KSR), but also put a special focus on the function of the recently identified or less studied scaffolders, such as fibroblast growth factor receptor substrate 2, flotillin-1 and mitogen-activated protein kinase organizer 1. WebRecombinant protein within human Erlin-2 aa 50-200 (Lumenal). ... SPFH domain family, member 2; SPFH domain-containing protein 2; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; UNQ2441 基因别名: BC036333; C87251; C8orf2; Erlin-2; ERLIN2; NET32; SPFH2; SPG18; UNQ2441/PRO5003/PRO9924

WebThe flotillin family is composed of two highly homologous proteins, flotillin-1 and flotillin-2 that share ~50% amino acid sequence similarity. ... Human Flotillin-1 recombinant protein corresponding to amino acids 1-270 expressed in E. coli. Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The ...

WebRecent work has provided new insights into the trafficking and targeting of flotillin and other PHB domain proteins. While the function of this large family of proteins remains unclear, …

WebThe flotillin (reggie) like proteins are lipid raft-associated. Individual proteins of this SPFH family may cluster to form membrane microdomains which may in turn recruit … how to run pcsx2 smoothlyWebThus, flotillin-1 represents a new integral membrane protein marker for the slightly larger caveolae-related domains (50–200 nm) that are observed in cell types that fail to express caveolin-1. As a consequence of these findings, we propose the term “cavatellins” be used (instead of flotillins) to describe this gene family. northern tales 2 level 40WebMay 24, 2016 · Flotillin-1 (Flot1, reggie-2) is a lipid raft-associated scaffolding protein that belongs to a family of proteins characterized by an evolutionarily conserved SPFH domain (Browman et al., 2007; Langhorst et al., 2008).Although flotillin-1 is ubiquitously expressed, it is known to be highly expressed in brain tissue, and has been shown to serve distinct … northern tales 2 level 15WebFlotillin is a family of lipid-membrane-associated proteins found in bacteria, archaea and eukaryotes. The family is found in association with pfam01145, another integral … how to run pdisk link on pcWebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … how to run perfinsight azureWebMar 21, 2024 · Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade; ... ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes; northern tales 2 level 25WebJun 26, 2013 · Background The flotillin family member flotillin-1 (FLOT1) encodes a caveolae-associated, integral membrane protein that belongs to lipid raft family and involves in vesicular trafficking and signal transduction. However, the role of FLOT1 in development and progression of cancer remains largely unknown. The present study … how to run pencil 2d