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Fun14 domain-containing protein 2

WebThe results of the current study revealed an interaction between the TPR domain of KLC1 and FUN14 domain-containing protein 1 (FUNDC1), which is a mitochondrial outer membrane protein mediating hypoxia-induced mitophagy. FUNDC1 bound to the six TPR motif-containing regions of KLC1 and did not interact with KIF5B (a motor subunit of … WebFUN14 domain-containing protein 2 is a protein that in humans is encoded by the FUNDC2 gene. References Further reading. This page was last edited on 27 March 2024, at 08:09 (UTC). Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms ...

FUNDC2 Gene - GeneCards FUND2 Protein FUND2 …

http://www.informatics.jax.org/marker/MGI:1914641 WebDescription: Homo sapiens FUN14 domain containing 1 (FUNDC1), mRNA. (from RefSeq NM_173794) RefSeq Summary (NM_173794): This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]. Gencode Transcript: ENST00000378045.5 chilly vertaling https://retlagroup.com

Full article: Dimerization of mitophagy receptor BNIP3L/NIX is ...

WebFUNDC2, FUN14 domain containing 2. Synonyms DC44, HCBP6, HCC3, PD03104 Links HGNC:24925. NCBI Gene ID: 65991. neXtProt AC ... protein-containing complex. synapse. vacuole. Click cells to view annotations. Expression less. Expression Overview early conceptus ... WebOrthologous to human FUNDC1 (FUN14 domain containing 1); PARTICIPATES IN mitochondrial autophagy pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; … WebDec 1, 2024 · Another mitophagy receptor activated by hypoxia is FUNDC1 (FUN14 domain-containing protein 1) [39, 40]. In response to hypoxia, FUNDC1 binds to MAP1LC3B via its LIR motif and facilitates mitophagy through autophagosome formation . Phosphorylation of FUNDC1 at a tyrosine residue in the LIR motif by SCR1 kinase … grade 12 life science study notes

Human Gene FUNDC1 (ENST00000378045.5) from GENCODE V43

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Fun14 domain-containing protein 2

65991 - Gene ResultFUNDC2 FUN14 domain containing 2 …

WebBNIP3L, a single pass OMM protein, requires its transmembrane domain (TM) for proper OMM localization [Citation 24]. Moreover, studies have shown that BNIP3L is a 24-kDa protein, which is predominantly expressed as a 48-kDa dimer, suggesting that BNIP3L dimerization might have a functional role [Citation 5, Citation 25]. As the molecular ... WebNX_Q9BWH2 - FUNDC2 - FUN14 domain-containing protein 2 - Function. Unknown function

Fun14 domain-containing protein 2

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WebNov 22, 2024 · PINK1–Parkin independent mitophagy employs several receptors: BNIP3 (Bcl-2/adenovirus E1B protein interacting with protein 3), Nix/BNIP3L (Nip3-like protein X), FUNDC1 (FUN14 domain-containing protein 1), and cardiolipin. They are localized in mitochondria and interact with LC3, attracting autophagosomes to damaged mitochondria. Web(Click on the icon in the table below to see search hit context)

WebSep 1, 2024 · FUN14 domain-containing 1 (FUNDC1) is a newly identified mitochondrial outer membrane protein that induces receptor-mediated mitophagy by its interaction … WebOct 17, 2024 · Several receptors of an independent form of mitophagy have been identified to date: BNIP3 (Bcl-2/adenovirus E1B protein-interacting protein 3), Nix/BNIP3L (Nip3-like protein X), FUNDC1 (FUN14 domain containing 1), cardiolipin .

WebSep 26, 2003 · DDRGK domain-containing protein 1 Curated. Alternative names. Dashurin 1 publication. UFM1-binding and PCI domain-containing protein 1 By similarity. Gene names. Name. DDRGK1 1 publication. Imported. Synonyms. C20orf116 Imported, UFBP1 By similarity. Organism names. Organism. Homo sapiens (Human) http://m.labbase.net/IndustryNewsDetial-140597.html

WebBackground/Purpose: Synovial fibroblast-like synoviocytes (FLSs) actively participate in the pathogenesis of rheumatoid arthritis (RA). FUN14 domain-containing protein 1 (FUNDC1), a novel mitophagy receptor, plays critical roles in receptor-mediated mitophagy and participates in pathogenesis of a variety of diseases. However, the roles of FUNDC1 and …

grade 12 life orientation term 1 notesWebJul 14, 2024 · Molecular pathways such as the signal pathways with the involvement of PTEN-induced putative kinase protein 1 (PINK1)/Parkin, BCL2/adenovirus E1B 19kDa-interacting protein 3/Nip3-like protein X (Bnip3/Nix), and FUN14 domain containing 1 (FUNDC1) are mainly responsible for regulating mitophagy. chilly voucher codeWebConserved Protein Domain Family. FUN14. Entrez: CDD: Structure: Protein: Help? pfam04930: FUN14 Download alignment. FUN14 family. This family of short proteins are found in eukaryotes and some archaea. Although the function of these proteins is not known they may contain transmembrane helices. Links? Source: pfam: Taxonomy: cellular … grade 12 life science study guide downloadWebNov 25, 2016 · The results of the current study revealed an interaction between the TPR domain of KLC1 and FUN14 domain‑containing protein 1 (FUNDC1), which is a mitochondrial outer membrane protein mediating hypoxia‑induced mitophagy. FUNDC1 bound to the six TPR motif-containing regions of KLC1 and did not interact with KIF5B … chilly vlogsWebRecently, FUN14 domain-containing protein 1 (FUNDC1) has been identified as a new outer mitochondrial membrane protein localized in MAMs [20,21]. FUNDC1 regulates the MAM formation responsible for Ca2+ release from the ER into mitochondria and cytosol in mouse cardiomyocytes. Moreover, overexpression of FUNDC1 was sufficient chilly vibeWebOrthologous to human FUNDC2 (FUN14 domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine. Type: protein-coding … grade 12 life sciences topic test pdfWebSep 1, 2024 · FUN14 domain-containing 1 (FUNDC1) is a newly identified mitochondrial outer membrane protein that induces receptor-mediated mitophagy by its interaction with LC3 during hypoxia. The expression ... grade 12 literacy assessment bc